胡小燕,张华,荣瑗瑗,张苗海,张向农
HU Xiao-yan,ZHANG Hua,RONG Yuan-yuan,ZHANG Miao-hai,ZHANG Xiang-nong

• 1:青岛市市立医院

摘要(Abstract)：

观察中西医结合治疗2型心肾综合征的临床疗效。将入选的2型心肾综合征患者分为单纯西医治疗组(对照组)和中西医结合治疗组(治疗组),2组患者均采用西医常规治疗,治疗组在此基础上给予补心益肾汤口服,共治疗3个疗程,观察2组患者治疗前后的总疗效、心功能指标、肾功能指标的变化情况。治疗组与对照组的总疗效分别为91.80%,72.41%。2组比较有显著性差异(P<0.01);组内比较,治疗组与对照组在治疗前后的心功能指标、肾功能指标都有明显改善,差异有统计学意义(P<0.01);2组治疗后心、肾功能指标比较,左室功能、血尿钠肽、血肌酐、尿素氮、胱抑素-C的改善,治疗组均优于对照组(P<0.05~0.01)。结果表明,中西医结合治疗能提高2型心肾综合征的临床疗效,明显改善心肾功能,优于单纯的西医常规治疗,且具有良好的安全性。
Clinical observation on treatment of type 2 cardiac and kidney syndrome by combination of traditional Chinese and Western medicine. The patients were divided into two groups: the simple Western medicine treatment group( control group) and the traditional Chinese medicine and Western medicine treatment group( treatment group). The patients in the two groups were treated with conventional western medicine. The treatment group was given based on Buxin Yishen decoction,a total of three courses of treatment to observe the two groups of patients before and after treatment of total efficacy,cardiac function indicators,changes in renal function indicators. The total efficacy of the treatment group and the control group were 91. 80% and 72. 41%,respectively. There were significant differences between the two groups( P < 0. 01). The cardiac function indexes and renal function indexes of the treatment group and the control group before and after treatment( P < 0. 01). Compared with the two groups,the left ventricular function,Hematuria natriuretic peptide,serum creatinine,urea nitrogen,cystatin-C were improved,and the treatment group( P < 0. 05 ~ 0. 01). The results showed that the combination of traditional Chinese and Western medicine treatment can improve the clinical efficacy of type 2 heart and kidney syndrome,significantly improve heart and kidney function,better than conventional Western medicine treatment,and has good safety.

关键词(KeyWords)： 中西医结合治疗;心肾综合征;疗效
combination of traditional Chinese and Western medicines;cardiac and kidney syndrome;curative effect

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(81300695)

作者(Author): 胡小燕,张华,荣瑗瑗,张苗海,张向农
HU Xiao-yan,ZHANG Hua,RONG Yuan-yuan,ZHANG Miao-hai,ZHANG Xiang-nong

DOI: 10.19540/j.cnki.cjcmm.20170901.009

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